| 5.8S ribosomal RNA |
 |
| Type: |
Gene; rRNA; |
| 2° structure: |
Published; PubMed |
| Seed alignment: |
Wuyts et al, European LSU rRNA database1 |
| Avg length: |
153.4 nucleotides |
| Avg identity: |
78% |
|
5.8S ribosomal RNA (5.8S rRNA) is a component of the large subunit of the eukaryotic ribosome. It is transcribed by RNA polymerase I as part of the 45S precursor that also contains 18S and 28S rRNA. Functionally, it is thought that 5.8S rRNA may be involved in ribosome translocation.2 It is also known to form covalent linkage to the p53 tumour suppressor protein.3 5.8S rRNA is also found in archaea.
References
- ^ Wuyts, J; De Rijk P, Van de Peer Y, Winkelmans T, De Wachter R (2001). "The European Large Subunit Ribosomal RNA Database". Nucleic Acids Res 29: 175–177. doi:10.1093/nar/29.1.175. PMID 11125083.
- ^ Abou, Elela S; Nazar RN (1997). "Role of the 5.8S rRNA in ribosome translocation". Nucleic Acids Res 25: 1788–1794. doi:10.1093/nar/25.9.1788. PMID 9108162.
- ^ Fontoura, BM; Atienza CA, Sorokina EA, Morimoto T, Carroll RB (1997). "Cytoplasmic p53 polypeptide is associated with ribosomes". Mol Cell Biol 17: 3146–3154. PMID 9154813.
External links
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